Sulforaphane: Its “Coming of Age” as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease

Cell-Logic, Sulforaphane: Its “Coming of Age” as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease

Abstract: A growing awareness of the mechanisms by which phytochemicals can influence upstream endogenous cellular defence processes has led to intensified research into their potential relevance in the prevention and treatment of disease. Pharmaceutical medicine has historically looked to plants as sources of the starting materials for drug development; however, the focus of nutraceutical medicine […]

It’s time to let your cells dwell well!

Cell-Logic, It’s time to let your cells dwell well!

Good Health Begins with Our Cells Our modern-day epidemic of chronic diseases has taken yet another ugly twist, presented by the dilemma of ‘overabundance’ — too many wrong choices and too few right ones. Although it’s fair to say that developed countries no longer face the stress of war or starvation, our cells still continue […]

Antioxidants — time to reconsider the principles? Part 1

Antioxidants — time to reconsider the principles? Part 1

For around six decades, we have indulged in a passionate love affair with ‘antioxidants’.  It seems we just can’t get enough of these seemingly miraculous compounds that are claimed to prevent disease, prolong our lives and keep us young.  Although that love affair has been souring for more than 20 years in scientific circles, the […]

EnduraCell Highest Sulforaphane Yielding Broccoli Sprout Powder

Cell-Logic, COVID-19 fallout

Independent scientific tests confirm that EnduraCELL yields 3.5 times more Sulforaphane per gram and dose than any other broccoli sprout product on the market. Every single batch of EnduraCell is assayed to provide its Sulforaphane Yield EnduraCell consistently yields Sulforaphane levels that can readily match the doses used in a range of clinical trials. What this […]

Nutrigenomics: the key to ageing gracefully

Nutrigenomics: the key to ageing gracefully

If you’ve ever wondered why some people are better able than others to retain their good health while they age, you probably won’t be surprised to know the answer lies in their genes. But while our actual DNA is non-negotiable—and determines what genetic issues we’re likely to have to deal with as we grow older—our […]

Sulforaphane and Other Nutrigenomic Nrf2 Activators: can the Clinician’s Expectation Be Matched by the Reality?

Cell-Logic, Sulforaphane and Other Nutrigenomic Nrf2 Activators: can the Clinician’s Expectation Be Matched by the Reality?

Abstract: The recognition that food-derived nonnutrient molecules can modulate gene expression to influence intracellular molecular mechanisms has seen the emergence of the fields of nutrigenomics and nutrigenetics. The aim of this review is to describe the properties of nutrigenomic activators of transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2), comparing the potential for sulforaphane […]

Sulforaphane: translational research from laboratory bench to clinic

Cell-Logic, COVID-19 fallout

Abstract: Cruciferous vegetables are widely acknowledged to provide chemopreventive benefits in humans, but they are not generally consumed at levels that effect significant change in biomarkers of health. Because consumers have embraced the notion that dietary supplements may prevent disease, this review considers whether an appropriately validated sulforaphane-yielding broccoli sprout supplement may deliver clinical benefit. […]